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The unfolded protein response is activated in disease-affected brain regions in progressive supranuclear palsy and Alzheimer’s disease

Lauren D Stutzbach, Sharon X Xie, Adam C Naj, Roger Albin, Sid Gilman, PSP Genetics Study Group, Virginia M Y Lee, John Q Trojanowski, Bernie Devlin and Gerard D Schellenberg*

Acta Neuropathologica Communications 2013, 1:31  doi:10.1186/2051-5960-1-31

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Correction to final paragraph of the discussion

Lauren Stutzbach   (2013-08-22 11:26)  University of Pennsylvania School of Medicine

The authors regret a typographical error in the final paragraph of the discussion section of this manuscript. In the following sentences, haplotype B is incorrectly identified: "The two low risk haplotypes (haplotype A, Ser-Arg-Ser; and haplotype B , Ser-Gln-Ser) differ only at the middle amino acid, 166- this amino acid is unlikely to functionally influence PERK activation. The low and high risk (Haplotype B, Cys-Gln-Cys ) haplotypes differ at both positions 166 and 704..."

Haplotype D, Ser-Gln-Ser, is a low risk haplotype. Haplotype B, Cys-Gln-Ala (not Cyn-Gln-Cys as the above sentence states), is the higher risk haplotype. We apologize for any confusion.

Competing interests

None declared


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